Possible Interaction: Alkaline Phosphatase and Catechin

“In addition, C did not change Km value of the AP-ase but it decreased its Vmax to 46% and 15% of the control when added in the assay or injected s.c.,”

“We have confirmed the suggestion by showing that C had profound effect on the process of de morn synthesis of certain plasma membrane-anchored enzymes, including alkaline phosphatase (AP-ase).”

“Compared with group A, the serum levels of ALP in group B and C were significantly higher, whereas the serum levels of ALP in group C seems to be higher than B (p < 0.05).”

“Elevated levels of alkaline phosphatase in the I/R group was significantly lowered (P < 0.01) by (+)‐catechin.”

“ (+)-Catechin caused a significant elevation of cell survival at 10(-5) and 10(-4) M and alkaline phosphatase activity at 10(-5) M. Also, treatment with (+)-catechin (10(-5) M) decreased bone-resorbing cytokines (TNF-alpha and IL-6) production and apoptosis in osteoblasts.”

“The effect of enterprises induced significant changes in the chemical composition and organic matter which in turn influenced the activities of enzymes (urease, acid, and alkaline phosphatase ) involved in the C , N, and P cycles.”

“… AP was excised … opposite C located next to four G.C base pairs than when correctly paired opposite T next to four A.T base pairs, suggesting … may be enhanced to a much greater extent by instabilities of local primer termini than by specific recognition of incorrect base pairs.”