Possible Interaction: Alkaline Phosphatase and Calcium Supplement

“In this sample, ALP activity was increased approximately by 60%, and calcium accumulation was approximately 6-fold above the negative control, indicating high osteogenic potential.”

“Six weeks of supplementation of iron and calcium individually, significantly reduced the activity of liver and serum superoxide dismutase and alkaline phosphatase.”

“The probability is discussed that the antagonism between the effects of calcium and sodium on the course of the AP of the guinea pig cardiac muscle (rate of depolarisation, rise time and AP duration) is due to opposite influences on the sodium conductance by both ions.”

“With increasing calcium concentrations the duration of the AP is at first slightly lengthened and then (above 1.2 mM with 140 mM Na+ and 0.6 mM with the 70 mM Na+ series) shortened.”

“The inhibitory effects on calcium accumulation and alkaline phosphatase activity are greater than those achieved by inactivation of the matrix by protease digestion of the bone morphogenetic factors present in demineralized bone.”

“Patients with ALP ≥ 566 U/L had lower calcium compared to patients with ALP < 566 U/L up to a month after RFA (P < 0.05).”

“Our results suggest that the presence of calcium ions can cause increased AP fluctuations, which ultimately could lead to their relocation on the homodimer surface.”

“No significant postoperative change in vitamin D, calcium , or phosphate was observed, but alkaline phosphatase increased significantly (P < 0.001).”

“Calcium was shown to increase proliferation of cells, whereas both calcium and phosphate positively affected alkaline phosphatase enzyme production.”

“On multiple linear regression analysis, the total amount of injected calcium during hospitalization showed a significant correlation with preoperative ALP (p < 0.001), preoperative iPTH (p = 0.037), and Δphosphorus at 48 hours (p < 0.001).”

“ Calcium ions accelerate selective adsorption of AP on HAP and phosphate ions inhibit it.”