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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alkaline Phosphatase
supplement:
Caffeine
Research Papers that Mention the Interaction
“The addition of caffeine caused nearly identical prolongations of AP duration in MHS and MHN muscles.”
Abnormal Action Potential Responses to Halothane in Heart Muscle Isolated from Malignant Hyperthermia-susceptible Pigs“CONCLUSION These results provided evidence that ca feine in high concentrations can decrease cellular viability and ALP ac tivity in HGF.”
“Nevertheless, caffeine at 5 and 10 mm dramatically decreased the viability and ALP activity of the cells after 4 days such that, by day 9, the viability of cells declined to near zero in the 10 mm group.”
“ Caffeine increased the activities of antioxidant enzymes (SOD, GPx, CAT, GST), AST, ALT, ALP , neutral proteases, and protease inhibitors, and the concentrations of uric acid, triglycerides, cholesterol, glucose, and Ca2+.”
Unexpectedly strong effect of caffeine on the vitality of western honeybees (Apis mellifera)“Caffeine had biphasic effects: 0.1 mM caffeine significantly enhanced mineralization and alkaline phosphatase (ALP) activity.”
“Furthermore, the internal Ca2+ release by histamine (10(-5) M) and caffeine (25 mM), both of which share this internal Ca2+ pool with NE, was also inhibited by AP II.”
“Results and discussionThe results showed that the viability of the osteoblasts, the formation of ALP positive staining colonies and mineralization nodules formation in the osteoblasts cultures decreased significantly in the presence of 10 mM caffeine.”
Direct effects of caffeine on osteoblastic cells metabolism: the possible causal effect of caffeine on the formation of osteoporosis
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