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Last Updated: 3 years ago

Possible Interaction: Alkaline Phosphatase and Berberine

Research Papers that Mention the Interaction

Different concentrations of BBR significantly promoted the proliferation of HAOBs and increased the expression levels of ALP , osteocalcin (OCN), collagen type I alpha 1 (COL1A1), runt related transcription factor 2 (RUNX2), and osterix (OSX).
Pharmacology  •  2020  |  View Paper
The MTT colorimetric assay, alkaline phosphatase (ALP) activity, and staining tests revealed that berberine could promote hPDLC growth, increase the secretion of ALP in the culture medium, and enhance the formation of mineralized nodule, thus it is a potential osteoplastic ingredient.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences  •  2012  |  View Paper
ALP staining and ARS staining in groups treated by berberine were significantly darker than those of the control group, and ALP protein secretion in the experimental group was significantly up-regulated (P<0.05).
Shanghai kou qiang yi xue = Shanghai journal of stomatology  •  2021  |  View Paper
The results revealed that BBR significantly decreased the serum levels of alanine transaminase, aspartate transaminase and alkaline phosphatase , and increased those of glutathione and superoxide dismutase, but decreased malondialdehyde activity in hepatic tissue, and significantly decreased the reactive oxygen species level in hepatocytes.
Molecular medicine reports  •  2019  |  View Paper
Berberine also prevented the elevated levels of enzymes (alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase ) and the decrease in body weight and albumin.
Redox report : communications in free radical research  •  2017  |  View Paper
The daily ingestion of … 2 or 4 g BBR reduced (p < 0.05) plasma aspartate … (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) and increased (p < 0.05) the dynamic change in the liver activity index (LAI) and liver functionality index (LFI), implying its hepatoprotective effect on transition goats.
Animals : an open access journal from MDPI  •  2021  |  View Paper
The flanking bases of the AP site also produce some modifications of the berberine's emission behavior.
Organic & biomolecular chemistry  •  2012  |  View Paper