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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Alkaline Phosphatase and Apigenin

Research Papers that Mention the Interaction

Our results showed that apigenin treatment significantly increased alkaline phosphatase (ALP) activity and mineralization in hMSCs.
Molecular and Cellular Biochemistry  •  2015  |  View Paper
Our results showed that the administration of apigenin (5-100 μM) efficiently decreased (P < .05) cytotoxicity, oxidative, lysosomal and mitochondrial damages induced by AlP (20 μg/ml) in isolated cardiomyocytes.
Pesticide biochemistry and physiology  •  2020  |  View Paper
In addition, treatment with apigenin resulted in a significant elevation of osteoblast differentiation genes including alkaline phosphatase (ALP), collagen, osteopontin (OPN), osteoprotegerin (OPG), bone sialoprotein (BSP), osterix (OSX) and osteocalcin (OC) and bone morphogenetic proteins (BMPs) genes (BMP2, BMP4 and BMP7).
International journal of molecular medicine  •  2014  |  View Paper
Apigenin (0.01 microM) significantly increased the growth of MC3T3-E1 cells and caused a significant elevation of alkaline phosphatase (ALP) activity and collagen content in the cells (P < 0.05).
Die Pharmazie  •  2007  |  View Paper