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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alkaline Phosphatase and Andrographolide

Research Papers that Mention the Interaction

Here we report the promoting effects of AP on the differentiation of mouse pre-osteoblastic (MC3T3-E1) cells by increasing the expression and activity of alkaline phosphatase (ALP), an osteoblastic gene-specific marker.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  •  2020  |  View Paper
We observed that 200 mg/kg andrographolide significantly decreased the level of alanine transaminase, aspartate aminotransferase, alkaline phosphatase , γ-glutamyltranspeptidase, total bilirubin, and total bile acid in the blood.
Journal of Natural Medicines  •  2018  |  View Paper
Results: Results showed that AP of 4.46 and 8.92 µM, especially 8.92 µM was beneficial to osteogenic differentiation by upregulating ALP activity and expression of osteogenic related genes (P<0.05).
Cellular Physiology and Biochemistry  •  2015  |  View Paper