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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Alkaline Phosphatase
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“The ACTH responses to hCRH and ITT in AP were higher (P<0.05) than in NS.”
Corticotrope hypersecretion coupled with cortisol hypo-responsiveness to stimuli is present in patients with autoimmune endocrine diseases: evidence for subclinical primary hypoadrenalism?“Our results suggest that ACTH increases the release of alkaline phosphatase by activation of a phospholipase C through cAMP and Gi which would contribute to produce IPG.”
ACTH stimulates the release of alkaline phosphatase through Gi-mediated activation of a phospholipase C and the release of inositolphosphoglycan“It was found that the release of alkaline phosphatase , a GPI-anchored enzyme, to the extracellular medium is increased in rat adrenocortical cells by ACTH treatment.”
“Second, the release of alkaline phosphatase , a GPI-anchored enzyme, to the extracellular medium was increased in these cells by ACTH.”
“injections of ACTH (10 micrograms-1 day-1) decreases were seen in both serum Alkaline phosphatase ( ALP ) activity and plasma trace metal concentrations; heart rate was significantly higher.”
“ ACTH treatment prevented the high levels of alkaline phosphatase activity which occurred between Days 3 and 7 of pregnancy in corpora lutea and follicles of control animals.”
“ ACTH initiates strong alkaline phosphatase activity in the connective tissue and blood sinuses of all cortical zones and in the connective tissue of the medulla.”
INFLUENCE OF HORMONES UPON THE DISTRIBUTION OF ALKALINE PHOSPHATASE IN MOUSE ADRENAL CORTEX
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