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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Alitretinoin
supplement:
Eb 1089
Research Papers that Mention the Interaction
“Furthermore, cotreatment of cells with 9-cis RA and EB1089 abrogates apoptosis.”
“We extend the study to show that EB1089 abrogates increases, induced by 9-cis RA , in caspase activation, p27Kip1 protein levels, Bim and Bax protein levels and in Bax/Bcl2 ratio.”
Investigation of the Mechanisms by Which EB1089 Abrogates Apoptosis Induced by 9-cis Retinoic Acid in Pancreatic Cancer Cells“The vitamin D3 analog, EB1089 , inhibited growth more effectively than 1,25-dihydroxyvitamin D3 and also acted synergistically with 9-cis-retinoic acid.”
“In the presence of 9-cis RA, EB1089 acted to further enhance the down-regulation and up-regulation of bcl-2 and p53 respectively.”
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