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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Aldosterone
supplement:
Vitamin D
Research Papers that Mention the Interaction
“In addition, an inverse relationship between 25-hydroxyvitamin D3 and aldosterone levels was observed (R = -0.4709, p = 0.0419).”
“In addition, an inverse relationship between 25-hydroxyvitamin D3 and aldosterone levels was observed (R = –0.4709, p = 0.0419).”
Effect of Short-Term Sunlight Exposure on Blood Pressure and Pulse Rate in Vitamin D3-Insufficient, Prehypertensive Patients: A Pilot Study“A new study suggests that vitamin D supplementation can lower systolic blood pressure and plasma aldosterone levels in patients with primary aldosteronism.”
“A nearly 20% effect of 25(OH)D on MAP was masked by aldosterone (total indirect effect: β = 0.01, P < 0.05).”
“The major finding was that vitamin D supplementation decreases plasma aldosterone.”
“ Aldosterone decreased in the vitamin D group (10.0 ± 11.9 to 6.2 ± 11.6 ng/dL) and not in the placebo group (8.9 ± 8.6 to 9.0 ± 12.4 ng/dL; P = .02).”
“For male patients, the aldosterone level with CC genotype was significantly higher than that of those with TT or TC genotype.”
“The aldosterone to renin ratio was 19% lower in the CC than in the TT genotype.”
“Medium supplementation with VEGF or aldosterone in combination with vitamin D3 resulted in the coordinated proliferation of endothelial cells in the explant.”
Stimulation of renal microvascular development under organotypic culture conditions“ Vitamin D increased adjusted 1,25(OH)2D concentrations significantly (mean treatment effect and 95% CI: 18.3 pmol/L,7.3 to 29.3 … RU/mL, −213 to 1585 RU/mL; P = 0.134), renin (312 mIU/L, −279 to 902 ng/L; P = 0.298), or aldosterone (−…).”
Effects of Vitamin D Supplementation on Renin and Aldosterone Concentrations in Patients with Advanced Heart Failure: The EVITA Trial
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