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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Aldosterone and Trypsin

supplement:

Trypsin

Research Papers that Mention the Interaction

Stimulation of aldosterone by a serine protease, trypsin , was first reported in 1982, although the mechanism of this effect was unclear.
The Journal of endocrinology  •  2001  |  View Paper
Preincubation of viable whole glandular tissue with trypsin significantly enhanced aldosterone output and eliminated the trypsin-releasable 18-OH-DOC pool in IEF gels of solubilized inner zone membranes.
The Journal of endocrinology  •  1995  |  View Paper
On the other hand, stimulation of short-circuit current by aldosterone or pyruvate (added to substrate-depleted, aldosterone-repleted bladders) was substantially reduced by prior trypsinization of the apical surface.
The Journal of general physiology  •  1983  |  View Paper