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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Aldosterone and Sphingosine 1-Phosphate

Research Papers that Mention the Interaction

Compared to saline-treated SD rats, plasma aldosterone increased by ~50 pg/mL after infusing S1P.
Here, we investigated whether sphingosine-1-phosphate S1P ), which has previously been linked to obesity, increases aldosterone release.
S1P induced a short-lasting increase in plasma aldosterone in obese, but not in lean SHRs.
We conclude that S1P is a local regulator of aldosterone production.
The Journal of endocrinology  •  2017  |  View Paper