Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Aldosterone and Sphingosine 1-Phosphate

Research Papers that Mention the Interaction

Compared to saline-treated SD rats, plasma aldosterone increased by ~50 pg/mL after infusing S1P.
Here, we investigated whether sphingosine-1-phosphate S1P ), which has previously been linked to obesity, increases aldosterone release.
S1P induced a short-lasting increase in plasma aldosterone in obese, but not in lean SHRs.
We conclude that S1P is a local regulator of aldosterone production.
The Journal of endocrinology  •  2017  |  View Paper