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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Aldosterone
supplement:
Perilla Frutescens
Research Papers that Mention the Interaction
“ S. frutescens extracts and SUB repressed NF-κB-driven gene expression without activating GRE-driven gene expression and while neither activated MR mediated gene transcription, both antagonized the effects of aldosterone via the MR.”
Sutherlandia frutescens modulates adrenal hormone biosynthesis, acts as a selective glucocorticoid receptor agonist (SEGRA) and displays anti-mineralocorticoid properties.
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