Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Aldosterone and Oleic Acid


Oleic Acid

Research Papers that Mention the Interaction

Both, glucocorticoids (dexamethasone, cortisol … mineralocorticoids (deoxycorticosterone and aldosterone ) as well as the estrogen β-estradiol and … enhanced the extent of Δ9 desaturation to oleic acid of the saturated precursors, whereas only the two mineralocorticoids affected the incorporation … the exogenous acid into total cellular lipids, thus promoting a little stimulation.
Molecular and Cellular Biochemistry  •  2004  |  View Paper
Within the phosphatidylethanolamine subclass, pretreatment of rats with aldosterone decreased the content of monounsaturated fatty acids (predominantly oleic and palmitoleic acid) and of n-3 fatty acids, and increased the content of saturated fatty acids (palmitic acid).
The Journal of Steroid Biochemistry and Molecular Biology  •  2000  |  View Paper
Addition of oleic or linolenic acid to washed cells inhibited both aldosterone and corticosterone production, although cells from hypoxic 7-day-old rats were less sensitive.
American journal of physiology. Regulatory, integrative and comparative physiology  •  2000  |  View Paper
Pretreatment of the rats with aldosterone led to a significant decrease in the percent distribution of palmitic, arachidonic, docosapentaenoic and docosahexenoic acids, with a concomitant increase in palmitoleic, oleic and linoleic acids in plasma and liver homogenates, microsomes and cytosol fractions.
Biochemistry international  •  1990  |  View Paper