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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Aldosterone and Melatonin



Research Papers that Mention the Interaction

A chronopilot ex vivo study "suggests" that melatonin chronomodulates mouse aldosterone production.
Chronobiologia  •  1993  |  View Paper
Melatonin caused a notable hypertrophy of zona glomerulosa cells and a significant rise in the plasma concentration of aldosterone in both groups of rats.
Experimental and clinical endocrinology  •  1988  |  View Paper
Addition of melatonin to beef adrenal slices (10.8–86.2 nmol/500 mg tissue) inhibited the transformation of carbon-labelled progesterone (2.5 nmol/500 mg tissue) to cortisol (inhibition: 33–63%) and to aldosterone (inhibition: 21–63%).
Journal of steroid biochemistry  •  1977  |  View Paper