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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Aldosterone
supplement:
Magnesium
Research Papers that Mention the Interaction
“ Aldosterone produces many harmful effects: magnesium loss , myocardial fibrosis, sympathetic activation, baroreflex dysfunction and ventricular arrhythmias.”
Two new culprits in cardiovascular disease: QT dispersion and aldosterone.“The data are consistent with the hypothesis that aldosterone affects the cellular homeostasis of magnesium , probably through modification of the activity of the Na(+)-Mg(2+) antiporter.”
“Furthermore, platelet magnesium showed a trend for negative association (p < 0.1) to plasma aldosterone and magnesium fractional excretion in multivariate analysis.”
“These data indicate that magnesium stimulates renin release through the elevation of prostaglandins and suppresses aldosterone production through the intracellular calcium mobilization.”
“These findings suggest a close relationship between changes in plasma aldosterone and magnesium.”
“Evidence has accumulated that aldosterone plays an important part in the regulation of magnesium metabolism in experimental animals.”
“Indications that aldosterone is closely linked with magnesium metabolism have existed since the first discovery of this hormone.”
“These studies suggest that aldosterone increases the clearance and excretion of magnesium and potassium in a parallel manner.”
“These data suggest that magnesium has an inhibitory action on aldosterone production in vitro and may be a physiological regulator of aldosterone production.”
Magnesium ion: a possible physiological regulator of aldosterone production.
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