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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Aldosterone
supplement:
Arachidonic Acid
Research Papers that Mention the Interaction
“Metabolites of arachidonic acid have been implicated in the regulation of aldosterone release.”
Metabolism of arachidonic acid by rat adrenal glomerulosa cells: synthesis of hydroxyeicosatetraenoic acids and epoxyeicosatrienoic acids.“Pretreatment of the rats with aldosterone led to a significant decrease in the percent distribution of palmitic, arachidonic , docosapentaenoic and docosahexenoic acids, with a concomitant increase in palmitoleic, oleic and linoleic acids in plasma and liver homogenates, microsomes and cytosol fractions.”
“Graded doses of arachidonic acid (10(-6)-10(-4)M) increased the production of corticosterone and aldosterone in a dose-dependent manner.”
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