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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Aldesleukin
supplement:
Xanthohumol
Research Papers that Mention the Interaction
“In the present study we show that XN inhibits the proliferation of mouse lymphoma cells and IL-2 induced proliferation and cell cycle progression in mouse splenic T cells.”
Anticancer agent xanthohumol inhibits IL-2 induced signaling pathways involved in T cell proliferation.“Here we demonstrate that XN has profound immunosuppressive effects on T cell proliferation, development of IL-2 activated killer (LAK) cells, cytotoxic T lymphocytes (CTLs), and production of Th1 cytokines (IL-2, IFN-γ and TNF-α).”
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