supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Aldesleukin
supplement:
Vitamin C
Research Papers that Mention the Interaction
“There was about 50% inhibition of IL-2 secretion in cell cultures with 0.125 mM AA when compared to controls without AA.”
Ascorbic acid does not modulate potassium currents in cultured human lymphocytes“It was found that ascorbic acid , when added to whole blood cultures at a very high concentration of 1 mM, inhibits interleukin-2 secretion by T cells (p<0.05).”
“Collectively, the data indicate that ascorbic acid selectively influences the proliferation of B lymphocytes and negatively acts on IL2 production by T lymphocytes when a threshold of saturation is exceeded.”
“The IL2 production induced by PWM (but not by concanavalin A (Con A) or phytohemagglutinin (PHA)) decreased at high AA (> 142 microM).”
Influence of ascorbic acid on the response to mitogens and interleukin production of porcine lymphocytes.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback