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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Aldesleukin
supplement:
Ginseng
Research Papers that Mention the Interaction
“ Ginseng treatment reduced the peripheral blood concentration of CD8+ T cells and increased mitogen-stimulated T cell production of interleukin-2 ex vivo.”
A randomized controlled crossover trial of the effect of ginseng consumption on the immune response to moderate exercise in healthy sedentary men.“ GB treatment induced up-regulation of co-stimulatory molecules in bone marrow-derived DCs (BMDCs).”
Ginseng Berry Extract Promotes Maturation of Mouse Dendritic Cells“The results revealed that expression of IL-2 and IFN-gamma mRNA were dose-dependently enhanced by the ethanol extract of ginseng.”
“ Ginseng could reduce the pathologic damage, neutrophil aggregation, proinflammatory factors, and pulmonary edema in vivo and inhibit the PI3K-Akt signaling pathway and MAPK signaling pathway through downregulating expressions of STAT3, VEGFA, FGF2, PIK3CA, MAPK1, and IL2.”
Elucidation of the Mechanism of Action of Ginseng Against Acute Lung Injury/Acute Respiratory Distress Syndrome by a Network Pharmacology-Based Strategy“In addition, ginseng reduces the expression levels of proinflammatory cytokines (IFN-γ, TNF-α, IL-2 , IL-4, IL-5, IL-6, IL-8) and chemokines produced by airway epithelial cells and macrophages, thus preventing weight loss.”
“The data show that intraperitoneal administration of KRG compromises MDSC function and induces T cell proliferation and the secretion of IL-2 and IFN-γ, while it does not exhibit direct cytotoxicity on tumor cells and reduced MDSC accumulation.”
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