Possible Interaction: Alcohols and Potassium

“2 The predominant effect … octanol (and the other alcohols ) was to cause an increase in … initial rate of decay of the transient potassium current together with a slight decrease in the rate of decay of later phases of the current, such that the current decay became markedly non‐monotonic.”

“The delay … the potassium current, which was systematically … by the two alcohols , the curve relating this delay to prepulse potential being shifted towards larger (positive) delays.(5)This high degree of … alcohol molecules modify several more or less independent mechanisms associated with the turning-on of the potassium current.”

“… alcohols were … the potassium conductance.(4)A detailed analysis of the time course of the turning-on of the potassium current for various pulse potentials in the … membrane potential values more positive than-20 mV, the time constant of activation was reduced in the presence of propanol or heptanol.”

“We show that strengthening the opposing potassium and proton electrochemical membrane gradients is a mechanism that enhances general resistance to multiple alcohols.”