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Last Updated: 3 years ago

Possible Interaction: Alcohols and Morphine

supplement:

Alcohols

Research Papers that Mention the Interaction

Of 27 compounds tested, monoterpenoid alcohols , such as borneol and iso-borneol, exhibited a strong inhibitory effect on morphine glucuronidation in rat liver microsomes (RLM), whereas we failed to detect any inhibitory effect of endogenous substances including amino acids and sugars.
These results demonstrate that dietary and supplementary monoterpenoid alcohols modify the pharmacokinetics and pharmacodynamics of morphine through inhibition of UGT2B7.
Biological & pharmaceutical bulletin  •  2012  |  View Paper