Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Alcohols and Glycerol

supplement:

Alcohols

supplement:

Glycerol

Research Papers that Mention the Interaction

The transport system could be specific for glycerol and some analogous compounds with hydroxyl groups, since glycerol uptake was inhibited by some alcohols and compounds related to glycerol, such as 1,2-propanediol and glycerol 3-phosphpate.
Biological & pharmaceutical bulletin  •  2006  |  View Paper
However, glycerol seems to negatively affect the antimicrobial efficacy of alcohols.
Antimicrobial Resistance & Infection Control  •  2019  |  View Paper
Furthermore, glycerol absorption was selectively inhibited by several alcohols , among which 1,3-propanediol caused the greatest inhibition, and also by glycerol-3-phosphate and voglibose, which are alcohol-related compounds analogous to glycerol.
Biological & pharmaceutical bulletin  •  2005  |  View Paper
For the monohydric alcohols used in this study (methanol, ethanol, 1-propanol, n-butanol, iso-butanol and trifluoroethanol), B22 for lysozyme reaches a common plateau at approximately 5% (v/v) alcohol, while glycerol increases B22 more than monohydric alcohols.
Biophysical chemistry  •  2004  |  View Paper
It is calculated that alcohols affect both the long-range interactions between phospholipids and proteins in mitochondrial membranes (as detected by spin labels) and the order of phospholipid bilayers near the glycerol region (as detected by ANS).
Archives of biochemistry and biophysics  •  1976  |  View Paper
These findings are consistent with the explanation that alcohols compete with glycerol (hence also with the glycerophosphate product) for a hydroxy binding site on the enzyme.
Biochimica et biophysica acta  •  1975  |  View Paper
Indeed, the catalytic etherification of glycerol with lessactivated alcohols , such as aliphatic alcohols, is thermodynamically much more difficult.
ChemSusChem  •  2011  |  View Paper