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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Alcohols
supplement:
Gamma-Aminobutyric Acid
Research Papers that Mention the Interaction
“Volatile anesthetics and alcohols enhance transmission mediated by γ-aminobutyric acid type A receptors (GABAARs) in the central nervous system, an effect that may underlie some of the behavioral actions of these agents.”
An Isoflurane- and Alcohol-Insensitive Mutant GABAA Receptor α1 Subunit with Near-Normal Apparent Affinity for GABA: Characterization in Heterologous Systems and Production of Knockin Mice“We have recently demonstrated that ethanol and longer-chain alcohols n-alcohols ) enhance gamma-aminobutyric acid (GABA)-induced chloride currents before desensitization takes place.”
Chloride current induced by alcohols in rat dorsal root ganglion neurons“ n-Alcohols , when added in increasing concentrations, had an unusual triphasic effect on the uptake of choline and of gamma-aminobutyric acid by isolated synaptosomes.”
“Inhibition of GABA release was found to be highly related to the membrane/buffer partition coefficient of n-alcohols.”
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