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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Albumin
drug:
Vincristine
Research Papers that Mention the Interaction
“Drugs used in combination with MTX in therapy vincristine , vinblastine, cyclophosphamide, 5-fluorouracil, prednisone) depress the MTX binding to albumins.”
Methotrexate binding to human plasma proteins.“These in vitro data show a previously unrecognized protective effect of increasing concentrations of albumin on the growth of human lymphoblastic leukemia cells exposed to VCR as a consequence of inhibition of drug uptake.”
“Chromatographic separation of the various secreted proteins showed that the release of albumin , globulins, and small polypeptides was decreased to a similar extent by vincristine or colchicine.”
Evidence for a role of the microtubular system in the secretion of newly synthesized albumin and other proteins by the liver.
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