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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Albumin
drug:
Teicoplanin
Research Papers that Mention the Interaction
“RESULTS At pH7 and 37°C the addition of al umin in creased median MICs four-fold, eight-fold and two-fold for telavancin, tei coplanin an d vancomycin, respectively.”
“While changing temperature or pH alone had a moderate impact, the combination of albumin addition, pH decrease and temperature increase led to the maximum reduction of activity of 16-fold for teicoplanin compared to the standard setting.”
Impact of different pathophysiological conditions on antimicrobial activity of glycopeptides in vitro.“Therefore, co-administration of TEIC may displace WF from the albumin binding site, and possibly result in a toxicity.”
“These observations suggested that TEIC can cause a rise in free WF concentration by albumin binding interaction.”
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