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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Albumin
drug:
Streptozocin
Research Papers that Mention the Interaction
“All multiple doses of STZ increased the albumin :creatinine ratio significantly, and immunohistochemical staining of KIM-1 and Ki-67 was increased by 5 × 50 and 2 × 100 mg/kg STZ.”
Optimising streptozotocin dosing to minimise renal toxicity and impairment of stomach emptying in male 129/Sv mice“ Ghost albumin excretion rate was enhanced 11-fold after 8 weeks of STZ diabetes as compared with aged-matched controls.”
“ Albumin permeability increased steadily from induction in streptozotocin-treated animals , reaching a plateau at approximately 120 h. Glomerular filtration rate was shown to increase significantly at approximately 7 days and proteinuria correlated with it.”
“injection of streptozotocin 50 mg/kg, reversed hyperglycemia, which would contribute to prevent the increases in urinary excretion rates of albumin and lipid peroxides observed in this experimental model.”
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