Possible Interaction: Albumin and Proline

“ Albumin at a concentration of 1 mg/ml increased the recovery of proline from the fraction by approx 2‐fold.”

“The possibility that albumin stimulates synaptosomal proline accumulation by virtue of its fatty acid binding property is discussed.”

“The inhibition of proline uptake (and that of the other Na+‐dependent amino acids) by oleic acid was … by the addition of serum albumin and the data presented further indicate that the previously reported stimulation of proline uptake by albumin could be related to its fatty acid binding properties.”

“Further, studies on the interaction of veratridine, valinomycin, and BSA on the uptake of proline suggest that the primary action of the albumin is to increase the influx of proline.”

“The amino acids, tryptophan, arginine, ornithine, lysine, phenylalanine, glutamine, alanine, threonine, and proline increased albumin synthesis toward or exceeding the value found in the fed control, and the endoplasmic membrane-bound polysome was reaggregated.”