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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Albumin
drug:
Poractant Alfa
Research Papers that Mention the Interaction
“ Curosurf and Survanta were dose-dependently inhibited by fibrinogen > haemoglobin > albumin , with far-reaching loss of surface activity at protein-surfactant ratios above 1:1.”
Surfactant inhibition by plasma proteins: differential sensitivity of various surfactant preparations.“Admixtures of plasma proteins albumin and fibrinogen) to Curosurf led to a controllable decrease in surface activity (i.e., adsorption and minimal surface tension of >25 and >5 mN/m, respectively), which served as models for dysfunctional lung surfactants.”
Biophysical Activity of Impaired Lung Surfactant upon Exposure to Polymer Nanoparticles.“ Albumin … Curosurf at both 2 and 3.5 mg/ml; this inactivation was prevented by 2% PxB. Treatment of newborn rabbits with Curosurf 80 mg/kg + 2% PxB significantly decreased incidence of pneumothorax in comparison with controls but had no significant effect on lung-thorax compliance or alveolar expansion.”
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