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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Albumin
drug:
Pancreatic Lipase
Research Papers that Mention the Interaction
“ Albumin , however, suppressed by 40% the stimulatory effect of Ca2+ on pancreatic lipase activity.”
Effect of sodium taurodeoxycholate, CaCl2 and albumin on the action of pancreatic lipase on droplets of trioleoylglycerol and the release of lipolytic products into aqueous media.“At concentrations greater than 1 mg/ml, albumin inhibited the activity of pancreatic lipase and interfered with enzyme binding to emulsified triacylglycerol particles.”
“It is concluded that … the inhibition of pancreatic lipase … albumin is due to the inaccessibility of the enzyme to an oil-water interface blocked by denatured albumin, then albumin saturated … oleic acid would seem to be protected from unfolding at the interface and more readily displaced by the lipase.”
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