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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Albumin and Octanoate



Research Papers that Mention the Interaction

Flow microcalorimetry data demonstrated a decrease in the ability of uraemic albumin to bind octanoate , phenol red, salicylic acid, warfarin and diazepam.
Nephron Physiology  •  2003  |  View Paper
The presence … mol of octanoate or decanoate … mol of albumin caused a decrease in dye binding (dye/protein molar ratio 1:1), which, in contrast with additional fatty acid, was … pronounced: 1-8 mol of palmitate or stearate resulted in a small, and apparently linear, displacement of Phenol Red.
The Biochemical journal  •  1981  |  View Paper
However, the oxidation of the medium chain fatty acid octanoate was inhibited in the presence of albumin over a broad range of octanoate concentrations (0.5-5.0 mM).
Biochimica et biophysica acta  •  2000  |  View Paper
At physiological albumin concentrations, the intracellular concentration of octanoate is only 7% of the extracellular concentration.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas  •  1989  |  View Paper
Hepatic ketogenesis was similar at 37 degrees with albumin , palmitate, or acetate, but was stimulated significantly by octanoate at 37 degrees and 42 degrees C. At 42 degrees, ketone formation increased in the presence of palmitate.
Cancer biochemistry biophysics  •  1985  |  View Paper