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Last Updated: 2 years ago

Possible Interaction: Albumin and Nitric Oxide

supplement:

Albumin

Research Papers that Mention the Interaction

However, inhaled NO increased the albumin lung leak index in this model (6.09+/-1.51 in the NO-treated group vs. 4.08+/-1.93 in the control group; P<0.05).
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery  •  2000  |  View Paper
This inhibitory effect appears to be a consequence of the direct antiplatelet actions of NO combined with the antiadhesive properties of albumin.
Journal of the American College of Cardiology  •  1999  |  View Paper
In vitro studies demonstrated that the decrease of sulfhydryl groups by NO or superoxide significantly attenuated SOQA of albumin.
Redox report : communications in free radical research  •  2004  |  View Paper
Accordingly, NO production (estimated by supernatant nitrite) was markedly (up to 10‐fold) increased in the presence of albumin.
British journal of pharmacology  •  2004  |  View Paper
The NO signal was markedly reduced in the presence of the protein albumin but not by either oxidized or reduced glutathione.
American journal of physiology. Lung cellular and molecular physiology  •  2001  |  View Paper
These results suggested that NO reacts with albumin-SH , resulting in albumin-S-NO formation, which produces a continuous hypotensive response in blood pressure as a slow releaser of NO.
Biochemical and biophysical research communications  •  1996  |  View Paper
The minimal effective NO perfusate concentration in the absence of endogenous NO synthesis was about 6 … nM, whereas a near-maximal effect was observed with approximately 200 nM. The presence of albumin reduced the speed of onset of renal vasodilation … the maximal effect at a given concentration of NO.
The Journal of pharmacology and experimental therapeutics  •  1995  |  View Paper
These data suggest an important role for NO in the regulation of albumin extravasation.
British journal of pharmacology  •  1993  |  View Paper
It is concluded that low molecular thiols and albumin may differently influence the detection of both NO and NO2- which derive from various NO donors or sodium nitrite.
Only the presence of 700 microns of albumin steadily suppressed the detection of NO or NO2- no matter what was the source of these species.
Polish journal of pharmacology  •  1997  |  View Paper