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Last Updated: 2 years ago

Possible Interaction: Albumin and Leukotriene B4

supplement:

Albumin

Research Papers that Mention the Interaction

Reduction of albumin in the buffer to 0.5% increased the apparent potencies of LTB4 and 6-cis-LTB1 five-fold.
Journal of immunological methods  •  1989  |  View Paper
Albumin , at concentration normally present in plasma (approximately 600 microM), significantly inhibited leukotriene B4 formation induced by a receptor mediated (fMet-Leu-Phe) and a receptor independent (calcium ionophore A23187) stimuli in human neutrophils.
Biochemical pharmacology  •  1989  |  View Paper
LTB4 release was increased in the presence of albumin , but was not affected by extracellular calcium or A23187.
Biochemical and biophysical research communications  •  1989  |  View Paper
It is suggested that binding of LTB4 to albumin in vivo will in part determine the available concentration of LTB4 in inflammatory lesions.
Prostaglandins  •  1987  |  View Paper
LTB4 and LTD4, 5-LO products, decreased the uptake of albumin in LLC-PK1 cells, a well-characterized porcine PT cell line.
PloS one  •  2014  |  View Paper
Protection at higher protein-concentration may be the result of LTB4 binding to albumin.
Journal of applied physiology  •  1988  |  View Paper