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“A negative correlation was established between itraconazole protein binding and albumin concentration, and a positive correlation with free fatty acid concentration.”
The Journal of antimicrobial chemotherapy • 1999 | View Paper
“The results from the in vitro drug delivery assay show the influence of albumin on the itraconazole delivery profile; a rapid release was observed for particles with higher albumin amount compared to those with lower protein content.”
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences • 2017 | View Paper
“Minimal inhibitory concentrations (MIC) of all strains tested to amphotericin B and itraconazole increased in the presence of physiological concentrations of human albumin.”