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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Albumin
drug:
Hypochlorite
Research Papers that Mention the Interaction
“Oxidation with hypochlorite was accompanied by a decrease in the effective concentration of albumin in albumin , diluted plasma, and serum and accumulation of carbonyl products of protein oxidation and bityrosine fluorescent products.”
“The decrease in the effective concentration of albumin during oxidation with hypochlorite can be explained by oxidative damage to albumin binding sites.”
Studies of oxidant-induced changes in albumin transport function with a fluorescent probe K-35. Effect of hypochlorite“We have determined the relative tendencies for formation of protein carbonyls, chlorinated tyrosine residues, and epitopes recognized by an antibody raised against hypochlorous acid oxidized protein (HOP-1) when albumin is treated with hypochlorous acid.”
Comparison of mono- and dichlorinated tyrosines with carbonyls for detection of hypochlorous acid modified proteins.“Pretreatment of some proteins albumin , immunoglobulin G, elastin and fibrinogen) with hypochlorite or with the MPO-H2O2-Cl- system increased their susceptibility to proteolysis by trypsin, chymotrypsin or elastase.”
Enhancement of proteinase-mediated degradation of proteins modified by chlorination.
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