supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Albumin
drug:
Hydrocortisone
Research Papers that Mention the Interaction
“Allosteric conformational changes may occur in albumin structure in the presence of cortisol.”
“Little or no displacement … protein binding sites on albumin occurred though a decrease in the number of binding sites (four vs two), and an increase in the affinity constant … interaction (4.32 X 10(2) vs 9.43 X 10(2) M-1) occurred in the presence of cortisol.”
Prednisolone binding to albumin and transcortin in the presence of cortisol.“In experiments where the concentration of cortisol was fixed there was striking evidence for the dependence of the interaction parameters on the concentration of albumin.”
“Since albumin binds cortisol less firmly than transcortin, the diffusible fraction of plasma cortisol increases (1-4).”
“ Hydrocortisone in not too small doses tends to increase the synovial permeability for albumin.”
“In the study of the dosage of modeling agent, TC and ALB may be affected more in the model of hydrocortisone and no indicators were significantly affected by the dosage of modeling agent in the dexamethasone model.”
[Mathematical analysis of characteristics of glucocorticoid-induced yang deficiency or yin deficiency syndrome in animal models based on information entropy theory].“The rate of production of albumin is stimulated 3- to 12-fold by adding hydrocortisone to the medium.2.The ninth component of complement (C9) is synthesized by MH1C1 cells, a finding which gives evidence that this trace complement component may be a liver product.”
“The effects of albumin on NHE3 protein abundance were modified by hydrocortisone in a complicated pattern.”
“ Albumin binds circulating glucocorticoids such as cortisol and consequently may modify the biological activity of these steroids by altering access to target cells.”
“We conclude that albumin enhances the negative feedback potency of cortisol in anterior pituitary corticotrophs and that the process may operate under physiological conditions to enhance cell specific delivery of this steroid to appropriate targets.”
“The results demonstrated that cortisol infusion decreased angiotensinogen mRNA by 61% in 138-d fetuses and albumin mRNA expression by 2.4-fold in 118-d fetuses and by 3.4-fold in 138-d fetuses.”
“ Hydrocortisone supplementation resulted in enhanced [3H]leucine uptake by the cells, inhibited in the presence of anti-rat albumin serum.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback