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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Albumin and Heparin

supplement:

Albumin

drug:

Heparin

Research Papers that Mention the Interaction

Therefore, we prepared albumins with clusters of negatively charged groups by coupling of heparin.
Biochemical pharmacology  •  2002  |  View Paper
While only a small percentage of albumin molecules underwent fragmentation in the presence of heparin with glucose, albumin turned out to display in an even higher proportion structural modifications consistent with a higher degree of ordered structure.
European journal of biochemistry  •  1997  |  View Paper
Addition of human albumin to fresh plasma collected into CPDA-1, citrate, or heparin (4 U/ml) resulted in an average of 2.8 fold (+/- 0.34 SD, n = 17) increase in yields of Cr fibrinogen.
Thrombosis research  •  1995  |  View Paper
Monochromatic measurement of albumin by the bromcresol green method leads to overestimation of albumin in the presence of heparin.
Clinical chemistry  •  1991  |  View Paper
Catheters coated with a conjugate of heparin and albumin showed a four- to five-fold reduction in platelet adhesion as compared to uncoated catheters.
Journal of biomedical materials research  •  1987  |  View Paper
Heparin can displace drugs from albumin by increasing free fatty acid concentrations, but this appears to be an in vitro artefact.
Clinical pharmacokinetics  •  1984  |  View Paper
Activation of protein kinase C, as well as an increase in intracellular cAMP, abolished this increase in albumin expression in the presence of heparin.
Soluble heparin enhanced albumin expression in hepatocytes.
We conclude that heparin induces albumin expression in hepatocytes and activation of protein kinase C or increased intracellular cAMP antagonize this effect.
Digestive Diseases and Sciences  •  2004  |  View Paper
Rabbit albumin enhanced the effect of heparin on the LPL activity, while heterologous protein, to the contrary, diminished it.
Voprosy meditsinskoi khimii  •  1985  |  View Paper
The amount of the adsorption of albumin and fibrinogen decreased with increasing graft amount and heparin content.
Journal of biomedical materials research  •  1998  |  View Paper