Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 months ago

Possible Interaction: Albumin and Glyburide



Research Papers that Mention the Interaction

The differences between the IDDM and NIDDM group probably occurred because 6 NIDDM patients were taking glibenclamide (7.0-10.5 mg/day) which is known to inhibit the glycosylation reaction of albumin.
International journal of clinical pharmacology, therapy, and toxicology  •  1993  |  View Paper
Addition of glibenclamide decreased internal pH (pHin), and addition of albumin reversed this drop by 50%.
Diabetes  •  2003  |  View Paper
In contrast, glibenclamide inhibition of recombinant KATP channels was dramatically suppressed by albumin (predicted free drug concentration <0.1%).
PloS one  •  2018  |  View Paper
Irradiation of [3H]glibenclamide at 254 or 300 nm in the presence of albumin resulted in covalent labeling of the albumin molecule.
FEBS letters  •  1988  |  View Paper