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“The results of this study indicate that the spacer entity between folic acid and the albumin binder is of critical importance with regard to the tissue distribution profile of the radiofolate.”
“Conclusions: Folic acid and vitamin B complex co-administration effectively lowers tHcy and hs‑CRP levels and increases albumin levels in stable hemodialysis subjects, underscoring their potential benefit to attenuate the state of inflammation and possibly improve the nutritional status in patients on hemodialysis.”
Current medical research and opinion • 2007 | View Paper
“In vivo, PGA significantly attenuated kidney injury and reduced blood urea nitrogen (BUN), serum creatinine (CREA) and urinary albumin ( Alb ), and increased creatinine clearance (CC) in IRI mice.”
“Similarly, the combination of S and FA significantly improved the concentrations of total protein, albumin , and globulin in serum, reduced the LP and increased the activity of GSHPx and LPR.”
“Altogether, we highlight a mechanism that FA reduces the plasma Hcy level and thereby enhance the bilirubin-binding ability of albumin , which may provide a novel therapeutic strategy for the treatment of pathological neonatal jaundice.”