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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Albumin
drug:
Epoprostenol
Research Papers that Mention the Interaction
“The addition of albumin reduced the amount of PGI2 formation elicited by HDL3 or LDL.”
Effect of human plasma lipoproteins on prostacyclin production by cultured endothelial cells.“Chemical analysis shows that vertebrate albumins prolong the half-life of prostaglandin I2.”
“Treatment of the cells with PGI2 or dibutyryl cAMP caused a significant inhibition of the thrombin-induced increase in the albumin permeability.”
“ Albumin at 40 mg/ml increased the KD of PGI2 binding to the receptors by 2-3 fold.”
“These findings indicate that albumin plays a major role in protecting PGI2 activity and regulating its availability for platelet PGI2 receptors.”
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