Possible Interaction: Albumin and Enalapril

“ Enalapril alone reduced total protein excretion (61% change from baseline) and fractional clearance of albumin without changes in GFR and minor elevation in renal plasma flow.”

“There was a significant fall in albumin excretion while patients were on enalapril , but in the nitrendipine group, neither albuminuria nor EGF excretion changed significantly.”

“ Enalapril resulted in an average reduction in urinary protein and albumin losses of 26% and 33%, respectively, without reducing creatinine clearance.”

“Treatment with either captopril, enalapril or lisinopril reduced albumin excretion rate in comparison with control patients.”

“Treatment with either captopril, enalapril or lisinopril reduced albumin excretion rate in comparison with control patients.”

“Treatment with either captopril, enalapril or lisinopril reduced albumin excretion rate in comparison with control patients.”

“Urinary protein excretion and fractional clearance of albumin were both significantly reduced by enalapril (basal 2.3 +/- 1.1 g/day and 102 +/- 90 x 10(-5), enalapril 1.2 +/- 0.6 g/day and 51 +/- 23 x 10(-5), respectively) and returned to basal values after enalapril withdrawal.”

“The clearance of albumin decreased significantly in ENAL (P < 0.001) and was significantly lower than in CON, HOE, or HOE/ENAL on Day 10.”

“UAlbV and the fractional renal clearance of albumin (FCAlb) decreased significantly after either phosphoramidon or enalapril , although only enalapril reduced blood pressure.”

“ Enalapril prevented … of albumin (FCalb) observed in HP (HP + enalapril, 136 +/- 44 mg/day and 0.88 +/- 0.54 X 10(-2), vs. HP, 368 +/- 60 mg/….90 X 10(-2), P less than 0.05 and P less than 0.05, respectively) but did not alter GFR significantly.”