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Last Updated: 2 years ago

Possible Interaction: Albumin and Dextran

supplement:

Albumin

drug:

Dextran

Research Papers that Mention the Interaction

A decrease …−1 after albumin infusion … of dextran caused a substantial increase in the renal clearance (from 84 to 123 ml·min−1), non-renal clearance (from 72 to … of distribution (from 13 to 23 l) of frusemide, probably as a consequence of an increase in the unbound fraction.
European Journal of Clinical Pharmacology  •  2004  |  View Paper
We have previously shown that an addition of dextran to surfactant increases resistance to inactivation by albumin.
Acta paediatrica  •  2000  |  View Paper
Albumin was used as a control of the volume-expanding effect of dextran.
Acta chirurgica Scandinavica  •  1985  |  View Paper
Significant reductions in that complication by albumin were also shown in subgroup analyses versus each of the other volume expanders tested (e.g., dextran , gelatin, hydroxyethyl starch, and hypertonic saline).
Hepatology  •  2012  |  View Paper
Albumin reduced viscosity and aggregation, but especially dextran 75 increased both parameters significantly.
Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete  •  1993  |  View Paper
The steric repulsion conferred by the presence of DEX at the surface of the nanoparticles decreased the adsorption of albumin.
Journal of controlled release : official journal of the Controlled Release Society  •  2005  |  View Paper
We hypothesized that albumin would decrease the hydraulic permeability (Lp) of isotonic and hypertonic solutions containing Dextran.
Shock  •  2003  |  View Paper
Indeed, dextran in the bath stimulated fluid absorption by 55% over albumin.
American journal of physiology. Renal physiology  •  2001  |  View Paper
The minimum surface tension of 2.0 mg/ml MNS with 30 mg/ml albumin decreased from over 21 mN/m to below 3 mN/m when dextran was added at a concentration of 10 mg/ml (P < 0.01).
The surface adsorption time of 0.5 mg/ml modified natural surfactant (MNS; porcine lung extract consisting of phospholipids and hydrophobic surfactant proteins) with 7.5 mg/ml albumin decreased from 681 to 143 s by addition of dextran at a concentration of 10 mg/ml (P < 0.01).
Journal of applied physiology  •  1999  |  View Paper
The results suggest that isovolemic hemodilution with both albumin and dextran is associated with a marked increase in blood flow in the rabbit.
Microsurgery  •  1995  |  View Paper
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