supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
Research Papers that Mention the Interaction
“We previously reported that mixed-disulfide formation of albumin with low molecular weight thiols, such as cysteine and glutathione, increased the affinity of this protein for phenolsulfophthalein (PSP) and Cu(II).”
Effect of nitric oxide on the ligand-binding activity of albumin.“It is known that albumin combines with cysteine in circulation to form albumin-Cys34-S–S-Cys.”
“3-Thio-2-hydroxypropyl-Sepharose showed very high selectivity for linkage of albumin at pH 8.1, while cysteine preferably linked α1AT and IgA. Substitution of the carboxylate group of cysteine increased the linkage of albumin.”
“ Albumin speeded up the spontaneous oxidation of both aminothiols, the reaction being faster with cysteine than with homocysteine.”
Oxidation of cysteine and homocysteine by bovine albumin.“Dialysis of albumin reduced its ability to support the effect of cysteine as did passage over Sephadex G-50.”
“The effect of albumin on the action of cysteine was biphasic.”
“ Cysteine (Cys) was used to break the disulfide bond of albumin and introduce the self-assembly of drug and albumin.”
A nontoxic disulfide bond reducing method for lipophilic drug-loaded albumin nanoparticle preparation: formation dynamics, influencing factors and formation mechanisms investigation.“Stronger neo‐minophagen C (SNMC) containing cysteine , a nucleophilic amino acid, has the potential to control the redox state of albumin.”
“ Albumin isomerizes to the aged form in the presence of cysteine at pH 8.9 and low ionic strength.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback