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Possible Interaction: Albumin and Cyclosporine

supplement:

Albumin

Research Papers that Mention the Interaction

A significant reduction of proteinuria and an increase of plasma albumin concentration was observed with treatment with cyclosporin.
British medical journal  •  1987  |  View Paper
Hematocrit (HCT), plasma albumin (ALB) level, and coadministration of itraconazole (ITR) were found to significantly affect the clearance of CsA (CL, L/h).
European Journal of Drug Metabolism and Pharmacokinetics  •  2012  |  View Paper
Treatment with cyclosporine and methylprednisolone significantly reduced albuminuria.
Medicina  •  2007  |  View Paper
RESULTS For cultured HepG2 cells, IL-6 significantly decreased albumin levels in a dose-… manner (P <0.01), and the maximal inhibition occurred at 5 microg/L. CSA mildly decreased albumin levels and a significant reduction in albumin production was first visible at 10 microg/ L (P <0.05).
RESULTS For cultured HepG2 cells, IL-6 significantly decreased albumin levels in a dose-… manner (P <0.01), and the maximal inhibition occurred at 5 microg/L. CSA mildly decreased albumin levels and a significant reduction in albumin production was first visible at 10 microg/ L (P <0.05).
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences  •  2006  |  View Paper
In contrast, CSA caused only a slight decrease in albumin levels (P < 0.05).
Inflammation Research  •  2006  |  View Paper
A weak, but significant, covariation was observed between the serum concentration of albumin or bilirubin and the free fraction of CyA (r = -0.47 and r = 0.39, respectively; p less than 0.01).
Therapeutic drug monitoring  •  1989  |  View Paper
Systolic and diastolic blood pressures as well as albuminuria were significantly higher in the offspring of mothers treated with CsA during gestation compared to the offspring from the control group.
Kidney & blood pressure research  •  2015  |  View Paper
These experiments suggest that the antiproteinuric effect of CsA is not (only) due to a decrease in the GFR, but also to a decrease of the enhanced permeability of the glomerular capillary wall for albumin.
Nephron  •  1997  |  View Paper
Albuminuria was substantially reduced by CsA (CsA 1.6 +/- 1.8; OO 5.6 +/- 3.2 mg/18 h; P < 0.002).
Although the CsA-induced GFR reduction was prevented, CsA still reduced albuminuria significantly (PB and CsA, 2.2 +/- 1.8; controls (PB and OO), 5.6 +/- 1.8 mg/18 h; P = 0.003).(ABSTRACT TRUNCATED AT 250 WORDS)
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association  •  1995  |  View Paper
Therapeutically administered dexamethasone (Dex) (0.1-1 mg/kg body weight) or cyclosporin A (CsA) (25-75 mg/kg body weight) dose-dependently reduced albumin movement across the blood-brain barrier (BBB).
International journal of immunopharmacology  •  1995  |  View Paper
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