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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Albumin and Chenodeoxycholate

supplement:

Albumin

Research Papers that Mention the Interaction

Four percent human albumin decreased the inhibitory effects of 100 μM chenodeoxycholic acid and lithocholic acid from 89.9 ± 5.6 to 54.5 ± 6.1 % and from 83.8 ± 4.8 to 20.8 ± 4.2 %, respectively.
Journal of Physiology and Biochemistry  •  2014  |  View Paper
Addition of albumin enhanced the partitioning of cholesterol out of the micelles in sodium chenodeoxycholate solution as a result of decreased micellar solubility and increased the aqueous solubility of cholesterol in the presence of albumin.
Biochimica et biophysica acta  •  1987  |  View Paper
Uptake was inhibited by albumin in the order chenodeoxycholic acid 3-sulphate greater than taurochenodeoxycholic acid 3-sulphate greater than taurochenodeoxycholic acid and was dependent on the extent of bile acid binding to albumin.
Biochimica et biophysica acta  •  1983  |  View Paper
Addition of albumin (1 g-%) increased the threshold dose of CDCA ; this occurred for TLCA only 8 g-%.
Klinische Wochenschrift  •  1981  |  View Paper