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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Albumin
drug:
Cefotaxime
Research Papers that Mention the Interaction
“Patients treated with cefotaxime had higher levels of plasma renin activity than those treated with cefotaxime and albumin ; patients with renal impairment had the highest values.”
Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis.“A previous study showed that cefotaxime plus albumin treatment decreased renal impairment more than antibiotic treatment alone in patients with serum bilirubin > 4 mg/dL or creatinine > 1 mg/dL. 4% Gelofusine is a colloidal volume replacement fluid used for fluid resuscitation and hemodynamic stabilization.”
“Human serum, serum alpha 1-, beta- and gamma-globulin fractions and albumin often antagonized or did not affect significantly the antimicrobial activity of cefotaxime , while the alpha 2-globulin fraction usually enhanced drug activity.”
Effect of blood product medium supplements on the activity of cefotaxime and other cephalosporins against Enterococcus faecalis.
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