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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Albumin
drug:
Carbamazepine
Research Papers that Mention the Interaction
“Use of 5% albumin dialysate further increased VPA and CBZ clearance.”
“We investigated whether the addition of albumin to dialysate affects dialytic clearance of VPA, CBZ and PHT.”
Enhanced clearance of highly protein-bound drugs by albumin-supplemented dialysate during modeled continuous hemodialysis.“… carbamazepine … albumin (B = -0.300, p = 0.040), calcium (B = -0.262, p = 0.004), phosphorus (B = -0.241, p = 0.022), WBC (B = -0.288, …), NEU% (B = -0.289, p = <0.001), LYM% (B = -0.268, p = 0.001), D vitamini (B = -0.344, p = 0.006) levels.”
“ Carbamazepine displaced some unknown compounds from their links with plasmatic albumin , thus allowing triptofane to link itsel.”
“In hydrated matrix tablets and aqueous solutions, EA influenced the conversion rate of CBZ to the dihydrate form depending on EA concentration.”
“It was found that increasing EA concentration enhanced CBZ dihydrate aggregation, an effect that leads to the formation of crystals with high mechanical strength and decrease of CBZ solubility.”
“The results suggest that in solid-state mixtures, EA affected the polymorphic transitions of CBZ from the beta to the alpha form.”
The effect of egg albumin on the crystalline properties of carbamazepine in sustained release hydrophilic matrix tablets and in aqueous solutions.
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