Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Naunyn-Schmiedeberg's Archives of Pharmacology • 2004 | View Paper
“Two months after capsaicin treatment a significant increase in albumin extravasation was found in the lower (P < 0.005), but not in the upper (5-8 cm from the anus) part of the colon as compared to the sham-operated control.”
“ Capsaicin (1 x 10(-6) M) was about 100 times less potent as a bronchoconstrictor when preincubated with albumin for 45 min, and the associated overflow of CGRP-LI was inhibited (from 221.0 +/- 63.4 fmol to 8 fmol fraction-1).”
“ Capsaicin was also less effective as a constrictor in isolated bronchi after preincubation with albumin , suggesting that capsaicin itself may be bound or absorbed to this macromolecule.”