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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“These two proteins positively interacted in the oxidation of ascorbate, since addition of crude albumin to a solution of ascorbate and ceruloplasmin increased the intensity of ESR signal in a dose-dependent manner.”
An electron spin resonance (ESR) study on the mechanism of ascorbyl radical production by metal-binding proteins“The albumin dimer did not form in plasma devoid of CO2 and its formation was enhanced by ascorbate.”
“Exposure of albumin to Cu(II) (10-100 microM) and ascorbate (0.1-2 mM) results in extensive molecular modifications, indicated by decreased fluorescence and chain breaks.”
“Human ceruloplasmin and albumin catalyzed singly ascorbate oxidation and caused a remarkable increase in ESR intensity of the ascorbate radical.”
“ Albumin treatments markedly attenuated interference from ascorbate catalytic effects whereas lipids enhanced both electrode capacitance and sensitivity to dopamine.”
Improved electrochemical properties of stearate-graphite paste electrodes after albumin and phospholipid treatments.“The addition of albumin , which is the main protein in serum, also inhibited H2O2 generation in the medium with ascorbate.”
“Excess ascorbate (as expected in intravenous treatment proposed for COVID-19 management, for example) oxidizes and/or degrades hemoglobin and albumin , as evidenced by UV-vis spectroscopy, gel electrophoresis, and mass spectrometry.”
Excess Ascorbate is a Chemical Stress Agent against Proteins and Cells“Pyridoxal, pyridoxal phosphate, ascorbate and dehydroascorbate, at concentrations of 0.1 mM or greater, significantly inhibited the nonenzymatic glycosylation of albumin.”
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