Possible Interaction: Albumin and Arginine

“ L-arginine caused a significant increase in urine flow, urinary excretion of albumin and sodium, and lithium clearance in all groups.”

“Infusion of 60 g of arginine in six healthy men over a 40-50 min period caused a 16-fold increase in the excretion-rate of albumin from 8-6 to 142-4 mug/min.”

“In addition, 3.17% Arg in the diet increased acid phosphatase and alkaline phosphatase activity in the hepatopancreas, as well as albumin concentrations in the haemolymph, when compared with the T-2 toxin group.”

“Dietary supplementation with l-arginine increased plasma concentrations of arginine, ornithine, proline, albumin and reticulocytes, while reducing plasma concentrations of ammonia, free fatty acids, triglyceride, cholesterol, and neutrophils.”

“While some amino acids are without effect on renal hemodynamics, arginine (Arg) augments renal blood flow and glomerular filtration rate, increases AlbSyn in tissue culture and isolated perfused livers, and could be one specific amino acid causing both decreased glomerular permselectivity and increased AlbSyn.”

“ Arginine supplementation during sepsis significantly increased (p < 0.05) albumin and liver protein synthesis compared with controls.”

“ Arginine supplementation during sepsis significantly increased (p less than 0.05) albumin and liver protein synthesis compared with controls.”

“Excess l‐arginine (2 × 10−3 M) inhibited the effect of native albumin and increased endothelial Lp 1.5 ± 0.02‐fold (P<0.05), but excess l‐lysine (4 × 10−3) in the presence of native albumin had no effect on Lp.”

“Intravenous infusion of arginine in humans was reported to induce a rapid increase of urinary excretion of albumin and a much greater increase of ß∑m [3].”

“Perfusion with arginine or ornithine increased albumin synthesis 3-fold compared with fasted control values.”