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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Albumin
supplement:
Arachidonate
Research Papers that Mention the Interaction
“ Albumin inhibits conversion of arachidonate to thromboxane A2 and hydroxy acids, especially at ratios of arachidonate/albumin below 10.”
“ Albumin relieves the inhibition caused by excess arachidonate , whether the stimulus is arachidonate itself or ADP.”
The modulation by serum albumin of rabbit platelet aggregation in response to exogenous sodium arachidonate.“2) Albumin enhanced release of arachidonate from phospholipids.”
“3) Albumin inhibited incorporation of arachidonate from the medium into platelet phospholipids.”
“We delineated three mechanisms by which albumin controlled platelet eicosanoid formation: 1) Albumin diverted free arachidonate toward 12-lipoxygenation.”
“ Albumin prevented 45Ca2+ release by arachidonate , presumably by binding the fatty acid.”
Mechanism of arachidonic acid-induced Ca2+ mobilization from rat liver microsomes.“30 min incubation of the strips with [3H]arachidonate complexed to albumin resulted in incorporation of this isotope into phospholipid and neutral lipid fractions, phosphatidylcholine greater than neutral lipid greater than phosphatidylserine plus phosphatidylinositol greater than phosphatidylethanolamine.”
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